Automated acquisition from multiple grids, including routines to align to a grid map and transform navigator items after reloading a grid and a flexible interface for managing the three stages of acquisition: grid mapping, medium mag mapping, and final acquisition Ability to align between images at different magnifications, used to enable Realign to Item to align to a medium mag map with a Preview image and to automate the finding of View and Search shift offsets Improvements in refining image shift vectors for Multiple Records: the Step To & Adjust IS procedure can be run automatically and can take a 2x2 montage to allow refining closer to the Record mag Options for autocontouring within a restricted area A new dialog for setting acquisition parameters for CTF-based coma and astigmatism routines, with some added options Redesign of the microscope control panel and some rearrangements in the microscope status panel Formatting in the log window with colored, bold, and underlined text and option to save the log as an RTF file to preserve this formatting Addition of 69 new script commands Nearly complete support for the UTAPI scriping interface, which will replace other interfaces in new ThermoFisher microscopes Conversion of open-source SerialEM repositories from Mercurial to git and availability on github